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(S)-MCPG
SKU
HY-100406-10 mg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mGluR, Neurological Disease
$79 – $436
Products Details
Product Description
– (S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371)[1]. (S)-MCPG can be used for the study of the function of mGluRs in spatial learning[2].
Web ID
– HY-100406
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H11NO4
References
– [1]Bernadett Boda, et al. Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome. Eur J Neurosci. 2014 Apr;39(7):1130-7.|[2]F Bordi, et al. Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning. Neuropharmacology. 1996;35(11):1557-65.
CAS Number
– 150145-89-4
Molecular Weight
– 209.20
Compound Purity
– 99.61
SMILES
– OC(C1=CC=C([C@](C)(N)C(O)=O)C=C1)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 1M NaOH : 22 mg/mL (ultrasonic;adjust pH to 11 with NaOH)
Target
– mGluR
Isoform
– mGluR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.