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S-Adenosyl-L-methionine (tosylate)

$84$336

Products Details

Product Description

– S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3].

Web ID

– HY-B0617A

Storage Temperature

– -20°C (Powder, stored under nitrogen, away from moisture)

Shipping

– Blue Ice

Applications

– COVID-19-immunoregulation

Molecular Formula

– C22H30N6O8S2

References

– [1]G M Bressa. et al. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14.|[2]Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6.|[3]Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92(4):1515-42.

CAS Number

– 52248-03-0

Molecular Weight

– 570.64

Compound Purity

– 98.92

SMILES

– O[C@@H]([C@H]([C@H](N1C=NC2=C(N=CN=C21)N)O3)O)[C@H]3C[S+](CC[C@H](N)C(O)=O)C.O=S(C4=CC=C(C)C=C4)([O-])=O

Clinical Information

– Launched

Research Area

– Cancer; Inflammation/Immunology; Neurological Disease

Solubility

– H2O : 150 mg/mL (ultrasonic)

Target

– Apoptosis;Endogenous Metabolite

Isoform

– Human Endogenous Metabolite

Pathway

– Apoptosis;Metabolic Enzyme/Protease

Product type

– Natural Products

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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