S-(2,4-Dinitrophenyl)glutathione

Products Details

Product Description

– S-(2,4-Dinitrophenyl)glutathione is a substrate for glutathione-S-transferase. (2,4-Dinitrophenyl)glutathione can be used as an irreversible glutathione reductase inhibitor with an Ki value of 30 µM[1][2].

Web ID

– HY-137330

Shipping

– Room temperature

Applications

– Metabolism-protein/nucleotide metabolism

Molecular Formula

– C16H19N5O10S

References

– [1]Yokooji T, et al. Site-specific bidirectional efflux of 2,4-dinitrophenyl-S-glutathione, a substrate of multidrug resistance-associated proteins, in rat intestine and Caco-2 cells. J Pharm Pharmacol. 2007 Apr;59(4):513-20.|[2]Bilzer M, et al. Interaction of a glutathione S-conjugate with glutathione reductase. Kinetic and X-ray crystallographic studies. Eur J Biochem. 1984 Jan 16;138(2):373-8.

CAS Number

– 26289-39-4

Molecular Weight

– 473.41

SMILES

– OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSC1=C(C=C(C=C1)[N+]([O-])=O)[N+]([O-])=O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease

Product type

– Peptides

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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