Download Files:
Products Details
Product Description
– RX-37 is a selective BET inhibitor. RX-37 binds to BET bromodomain proteins (BRD2, BRD3, and BRD4) with Ki values of 3.2-24.7 nM. RX-37 can be used for research of cancers[1].
Web ID
– HY-19549
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H23N5O2
References
– [1]Ran X, et al. Structure-Based Design of γ-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors. J Med Chem. 2015 Jun 25;58(12):4927-39.
CAS Number
– 1627715-60-9
Molecular Weight
– 413.47
SMILES
– COC1=CC2=C(NC3=C2C(C4=C(C)NN=C4C5CC5)=NC=C3)C=C1C6=C(C)ON=C6C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
