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Rutaecarpine
$42 – $290
Products Details
Product Description
– Rutaecarpine, an alkaloid of Evodia rutaecarpa, is an inhibitor of COX-2 with an IC50 value of 0.28 μM.
Web ID
– HY-N0147
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H13N3O
References
– [1]Moon TC, et al. A new class of COX-2 inhibitor, rutaecarpine from Evodia rutaecarpa. Inflamm Res. 1999 Dec;48(12):621-5.|[2]Lee SH, et al. Progress in the studies on rutaecarpine. Molecules. 2008 Feb 6;13(2):272-300.|[3]Jeon TW, et al. Immunosuppressive effects of rutaecarpine in female BALB/c mice.
Toxicol Lett. 2006 Jul 1;164(2):155-66.
CAS Number
– 84-26-4
Molecular Weight
– 287.32
Compound Purity
– 99.00
SMILES
– O=C1N2C(C(NC3=C4C=CC=C3)=C4CC2)=NC5=C1C=CC=C5
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– COX
Isoform
– COX-1;COX-2
Pathway
– Immunology/Inflammation
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
