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RSV-IN-5
Products Details
Product Description
– RSV-IN-5 (Compound 4) is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. RSV-IN-5 exhibits potent anti-RSV activities against not only wild-type A2 F protein (EC50=2.0 nM), but also D486N-mutant F protein (EC50=8.1 nM)[1].
Web ID
– HY-146108
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C28H37N7O2
References
– [1]Toru Yamaguchi-Sasaki, et al. Discovery of a potent dual inhibitor of wild-type and mutant respiratory syncytial virus fusion proteins through the modulation of atropisomer interconversion properties. Bioorg Med Chem. 2020 Dec 15;28(24):115818.
CAS Number
– 2415018-86-7
Molecular Weight
– 503.64
SMILES
– CN1C2=CC(N3CC[C@@H](C3)N)=NC4=CC([C@@]5([H])N(CCCC5)C(C6=CC(C)=CC=C6OCCCC1)=O)=NN24
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– RSV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.