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Products Details
Product Description
– RSK4-IN-1 is identified with potent RSK4 inhibitory activity with an IC50 value of 9.5 nM.
Web ID
– HY-132891
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H20F2N4O3
References
– [1]Yuan Y, et al. Discovery, Optimization, and Structure-Activity Relationship Study of Novel and Potent RSK4 Inhibitors as Promising Agents for the Treatment of Esophageal Squamous Cell Carcinoma. J Med Chem. 2021 Sep 23;64(18):13572-13587.
CAS Number
– 2755819-10-2
Molecular Weight
– 390.38
SMILES
– CC(C)(C1=CN=C(N=C1N2C3CCCC3)NC4=CC(F)=C(C(F)=C4)O)OC2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ribosomal S6 Kinase (RSK)
Isoform
– RSK4
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
