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RS100329 (hydrochloride)
$130 – $1,200
Products Details
Product Description
– RS100329 hydrochloride is a potent and selective α1A-adrenoceptor antagonist with pKi values of 9.6, 7.9 and 7.5 for α1A, α1D, and α1B, respectively. RS100329 hydrochloride inhibits reflex urethral contractions. RS100329 hydrochloride can be used in research of benign prostatic hyperplasia[1][2].
Web ID
– HY-103204
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C20H26ClF3N4O3
References
– [1]Conley RK, et, al. The role of alpha(1)-adrenoceptors and 5-HT(1A) receptors in the control of the micturition reflex in male anaesthetized rats. Br J Pharmacol. 2001 May;133(1):61-72.|[2]Williams TJ, et, al. In vitro alpha1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel alpha1A-adrenoceptor selective antagonists. Br J Pharmacol. 1999 May;127(1):252-8.
CAS Number
– 1215654-26-4
Molecular Weight
– 462.89
Compound Purity
– 99.57
SMILES
– O=C1N(CCCN2CCN(C3=CC=CC=C3OCC(F)(F)F)CC2)C(C(C)=CN1)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : 31.25 mg/mL (ultrasonic)
Target
– Adrenergic Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
