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RS-1
SKU
HY-19793-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage, CRISPR/Cas9;RAD51
$60 – $450
Products Details
Product Description
– RS-1 is a RAD51 activator, and also increases CRISPR/Cas9-mediated knock-in efficiencies.
Web ID
– HY-19793
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H16Br2N2O3S
References
– [1]Jayathilaka K, et al. A chemical compound that stimulates the human homologous recombination protein RAD51. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15848-53.|[2]Song J, et al. RS-1 enhances CRISPR/Cas9- and TALEN-mediated knock-in efficiency. Nat Commun. 2016 Jan 28;7:10548.
CAS Number
– 312756-74-4
Molecular Weight
– 524.23
Compound Purity
– 98.95
SMILES
– O=C(NC1=CC=C(Br)C=C1)C2=CC=C(Br)C(S(=O)(NCC3=CC=CC=C3)=O)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– CRISPR/Cas9;RAD51
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.