Download Files:
Products Details
Product Description
– RPR132595A (NPC) is an active metabolite of CPT-11, which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine[1].
Web ID
– HY-100638
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H30N4O6
References
– [1]Alvau MD, et al. Enzyme-Based Electrochemical Biosensor for Therapeutic Drug Monitoring of Anticancer Drug Irinotecan.Anal Chem. 2018 May 15;90(10):6012-6019.
CAS Number
– 185304-42-1
Molecular Weight
– 518.56
SMILES
– O=C(N1CCC(N)CC1)OC2=CC=C3N=C4C(CN5C(C(COC([C@@]6(CC)O)=O)=C6C=C54)=O)=C(CC)C3=C2
Clinical Information
– Phase 4
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
