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Rovanersen
SKU
HY-132593-10 mg
Category Oligonucleotides
Tags Huntingtin, Neurological Disease, Neuronal Signaling
$740 – $5,650
Products Details
Product Description
– Rovanersen (WVE-120101) is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen can be used for huntington’s disease research[1].
Web ID
– HY-132593
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C202H259N82O111P19S13
References
– [1]M Meena, et al. Selectivity and Biodistribution of WVE-120101, a Potential Antisense Oligonucleotide Therapy for the Treatment of Huntington’s Disease (S56.001). AAN Enterprises. April 18, 2017; 88 (16 Supplement).
CAS Number
– 2072901-32-5
Molecular Weight
– 6617.00
Compound Purity
– 94.24
SMILES
– [Rovanersen]
Clinical Information
– Phase 2
Research Area
– Neurological Disease
Solubility
– H2O : ≥ 50 mg/mL
Target
– Huntingtin
Pathway
– Neuronal Signaling
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.