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Products Details
Product Description
– Rovadicitinib hydrochloride is a JAK inhibitor with an IC50 value <20 nM. Rovadicitinib hydrochloride also exhibits anti-inflammatory activity[1][2].
Web ID
– HY-148798A
Shipping
– Room temperature
Molecular Formula
– C17H20ClN7
References
– [1]WHO Drug Informat ion – World Health Organization (WHO).|[2]Zhu Li, et al. Preparation of pyrrolopyrimidines as Janus kinase inhibitors: World Intellectual Property Organization, WO2016095805. 2016-06-23.|[3]WHO Drug Information-World Health Organization (WHO).
CAS Number
– 1948242-60-1
Molecular Weight
– 357.84
SMILES
– NC1=NN([C@@H](C2CCCC2)CC#N)C=C1C3=C4C(NC=C4)=NC=N3.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
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