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Products Details
Product Description
– Rostratin A is a cytotoxic disulfide found in the marine-derived fungus Exserohilum rostratum. Rostratin A shows in vitro cytotoxicity against human colon carcinoma (HCT-116) with an IC50 of 8.5 μg/mL[1].
Web ID
– HY-N10203
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H24N2O6S2
References
– [1]Tan RX, et al. Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produced by the marine-derived fungus Exserohilum rostratum. J Nat Prod. 2004;67(8):1374-1382.
CAS Number
– 752236-16-1
Molecular Weight
– 428.52
SMILES
– O=C(N1[C@@]([C@H](CC2)O)([H])[C@]([C@H]2O)([H])C3)[C@@]4(SS[C@]13C5=O)N5[C@@]([C@H](CC6)O)([H])[C@]([C@H]6O)([H])C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite
Isoform
– Microbial Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
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