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Product Description
– Rosamultic acid is an A-ring contracted triterpene, that can be isolated from the roots of Rosa rnultiflora. Rosamultic acid inhibits gastric cancer cells proliferation by inducing apoptosis mediated through cell cycle arrest, downregulation of cell cycle related protein expressions, inhibition of cell migration, DNA damage, and activation of caspases[1][2].
Web ID
– HY-122928
Shipping
– Room temperature
Molecular Formula
– C30H46O5
References
– [1]Yeo H, et al. A-ring contracted triterpenoid from Rosa multiflora[J]. Phytochemistry, 1998, 48(8):1399-1401.|[2]Sui CG, et al. Antiproliferative activity of rosamultic acid is associated with induction of apoptosis, cell cycle arrest, inhibition of cell migration and caspase activation in human gastric cancer (SGC-7901) cells. Phytomedicine. 2015 Aug 15;22(9):796-806.
CAS Number
– 214285-76-4
Molecular Weight
– 486.68
SMILES
– [H][C@]12CC=C3[C@@]4([C@@](C)([C@@H](CC[C@@](C(O)=O)4CC[C@]3([C@@](C)1CC[C@]5([C@@](C)(CO)C=C([C@@]52C)CO)[H])C)C)O)[H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Caspase
Pathway
– Apoptosis
Product type
– Reference compound
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