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Products Details
Product Description
– ROS-IN-2 (compound 85) is a seco-lupane triterpenoid derivative. ROS-IN-2 blocks ROS production and protects mitochondria from damage by inhibiting excessive production of oxidative stressors. ROS-IN-2 can be used for myocardial ischemia/reperfusion (MI/R) injury research[1].
Web ID
– HY-149586
Shipping
– Room temperature
Molecular Formula
– C42H62ClNO8S
References
– [1]Teng H, et al. Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-1α axis. Biomed Pharmacother. 2023 Nov;167:115452.
Molecular Weight
– 776.46
SMILES
– O=C(OCCC)CC1[C@]2(C)[C@]3([H])[C@@]([C@@](CC[C@]4(C(NCCOCCOC(C5=CC(Cl)=CS5)=O)=O)[C@]6([H])[C@H](C(C)=C)CC4)(C)[C@]6([H])C[C@H]3O)(C)CCC2C(C)(C)O1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
