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RORγt inverse agonist 23
SKU
HY-139847-10 mg
Category Reference compound
Tags Inflammation/Immunology, Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor, ROR
$300 – $2,400
Products Details
Product Description
– RORγt inverse agonist 23 is a potent, selective, and orally available novel retinoic acid receptor-related orphan receptor γt inverse agonist.
Web ID
– HY-139847
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H33NO5S
References
– [1]Chen L, et al. Discovery of Chromane-6-Sulfonamide Derivative as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist. J Med Chem. 2021 Nov 11;64(21):16106-16131.
CAS Number
– 2230779-18-5
Molecular Weight
– 471.61
Compound Purity
– 99.34
SMILES
– OC1C2=C(C=CC(S(N(C3=CC=C(CC)C=C3)C4CCC4)(=O)=O)=C2)OC(C5CCOCC5)C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : ≥ 100 mg/mL
Target
– ROR
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.