Products Details

Product Description

– Ropanicant (SUVN-911 free base) is a novel, potent, selective, and orally active neuronal nicotinic acetylcholine α4β2 receptor antagonist for the research of depression[1].

Web ID

– HY-139581

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C11H13ClN2O

References

– [1]Nirogi R, Mohammed AR, Shinde AK, Ravella SR, Bogaraju N, Subramanian R, Mekala VR, Palacharla RC, Muddana N, Thentu JB, Bhyrapuneni G, Abraham R, Jasti V. Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression. J Med Chem. 2020 Mar 26;63(6):2833-2853.

CAS Number

– 2414674-70-5

Molecular Weight

– 224.69

SMILES

– ClC1=NC=C(C=C1)OC[C@@H]2C[C@]3([H])[C@@](N2)([H])C3

Clinical Information

– Phase 1

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– nAChR

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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