Products Details

Product Description

– ROCK-IN-D2 is a potent and selective ROCK inhibitor[1].

Web ID

– HY-116238

Shipping

– Room temperature

Molecular Formula

– C22H28N6O

References

– [1]Ding Mei, et al. Discovery of potent and selective urea-based ROCK inhibitors: Exploring the inhibitor’s potency and ROCK2/PKA selectivity by 3D-QSAR, molecular docking and molecular dynamics simulations.Bioorg Med Chem. 2015 May 15;23(10):2505-17.

CAS Number

– 1219721-78-4

Molecular Weight

– 392.50

SMILES

– O=C(NCC1=CC=CC=C1)NC2=C(C=C(C=C2)C3=CNN=C3)N(C)CCN(C)C

Clinical Information

– No Development Reported

Research Area

– others

Solubility

– 10 mM in DMSO

Target

– ROCK

Pathway

– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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