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Products Details
Product Description
– ROCK-IN-8 (Example 4) is a ROCK inhibitor, with an IC50 value less than 100 nM. ROCK-IN-8 has anti-inflammatory activity. ROCK-IN-8 can be used for research of respiratory and gastro-intestinal diseases[1].
Web ID
– HY-156550
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C30H25FN4O4S
References
– [1]Sandro Boland, et al. Pyridine derivatives as soft rock inhibitors. Patent. WO2014118133.
CAS Number
– 1621103-79-4
Molecular Weight
– 556.61
SMILES
– O=C1OCCC1SC2=CC=C(C(NC3=CC(C4=CC(C(NC5=C(F)C=NC=C5)=O)=CC=C4CN)=CC=C3)=O)C=C2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
