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Products Details
Product Description
– ROCK-IN-6 is a potent and selectiveROCK2 inhibitor with an IC50 of 2.19 nM. ROCK-IN-6 is extracted from patent WO2021164351 A1, example 7, has the potential for glaucoma and retinal diseases research[1].
Web ID
– HY-153564
Shipping
– Room temperature
Molecular Formula
– C19H19N5O8S
References
– [1]Shen wang et al. Nitrooxyderivative of rock kinase inhibitor. Patent WO2021164351 A1
CAS Number
– 2489328-74-5
Molecular Weight
– 477.45
SMILES
– O=C(NC1=CC2=CC=NC=C2S1)C(C(C=C3)=CC=C3OCC(O[N+]([O-])=O)CO[N+]([O-])=O)CN
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– ROCK
Isoform
– ROCK2
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
