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Products Details
Product Description
– ROCK-IN-5 (compound I-B-37) is a potent inhibitor of ROCK, ERK, GSK, and AGC protein kinases. ROCK-IN-5 has the potential for proliferative, cardiac and neurodegenerative diseases research[1].
Web ID
– HY-153011
Shipping
– Room temperature
Molecular Formula
– C16H11ClFN3OS
References
– [1]Jingrong Cao, et al. Compositions useful as inhibitors of rock and other protein kinases. WO2004041813A1.
CAS Number
– 692870-25-0
Molecular Weight
– 347.79
SMILES
– O=C(NC1=NC(C2=CC=NC=C2)=CS1)CC3=C(F)C=CC=C3Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– ERK;GSK-3;ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;MAPK/ERK Pathway;PI3K/Akt/mTOR;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
