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Products Details
Product Description
– RO7185876 is a potent and selective gamma secretase modulator as a potential research for Alzheimer’s disease.
Web ID
– HY-145343
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C25H28F3N7
References
– [1]Ratni H, et al. Discovery of RO7185876, a Highly Potent γ-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer’s Disease. ACS Med Chem Lett. 2020 Apr 27;11(6):1257-1268.
CAS Number
– 2226038-71-5
Molecular Weight
– 483.53
SMILES
– FC(C(F)=C(C=C1)F)=C1[C@@]2([H])C3=NC(N[C@H]4[C@@H]5CN(C6=NC=NC(C)=C6)C[C@H]4CC5)=NN3CCCC2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– γ-secretase
Pathway
– Neuronal Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
