Ro 64-5229

$417$667

Products Details

Product Description

– Ro 64-5229 is a selective, non-competitive mGlu2 antagonist. RO 64-5229 reduces the presynaptic inhibitory effect of Neuroligin 1[1].

Web ID

– HY-103557

Shipping

– Room temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C17H19Cl2N3O

References

– [1]Gjørlund MD, et al. Soluble Ectodomain of Neuroligin 1 Decreases Synaptic Activity by Activating Metabotropic Glutamate Receptor 2. Front Mol Neurosci. 2017 May 3;10:116.

CAS Number

– 246852-46-0

Molecular Weight

– 352.26

SMILES

– ClC1=C(/C(OC2CCCCCC2)=C/N3N=CN=C3)C(Cl)=CC=C1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– mGluR

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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