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Products Details
Product Description
– RNase L-IN-1 (compound 17a) is an inhibitor of RNase L, or Ribonuclease L. RNase L degrades RNAs to prevent viral replication, and mediates the innate immune responses and inflammation[1].
Web ID
– HY-155583
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C27H35FN6O3S
References
– [1]Hwang J, et al. Rational design and evaluation of 2-((pyrrol-2-yl)methylene)thiophen-4-ones as RNase L inhibitors. Eur J Med Chem. 2023 Aug 5;256:115439.
Molecular Weight
– 542.67
SMILES
– O=C1/C(SC(NC2=CC(F)=CC=C2)=C1C(NCCN)=O)=CC3=C(C)C(C(NCCN(CC)CC)=O)=C(C)N3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
