RNase III

$80

Only 1000 item(s) left in stock.

Products Details

Product Description

– RNase III is a double-stranded RNA (dsRNA)-specific endonuclease from Escherichia coli expressing the RNase III gene. RNase III proteins are Mg2+-dependent endonucleases with a nine-residue signature motif, the RNase III domain. RNase III can cleave dsRNA into 12-15 bp small fragments of interfering RNA (siRNA), which are more suitable for RNA interference experiments in mammalian cells[1][2].

Web ID

– HY-E70092

Storage Temperature

– -20°C

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– N/A

References

– [1]Court DL, et al. RNase III: Genetics and function; structure and mechanism. Annu Rev Genet. 2013;47:405-31. |[2]Maurin T, et al. RNase III-independent microRNA biogenesis in mammalian cells. RNA. 2012 Dec;18(12):2166-73.

Molecular Weight

– N/A

Compound Purity

– 95.00

SMILES

– [RNase III]

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– DNA/RNA Synthesis

Pathway

– Cell Cycle/DNA Damage

Product type

– Biochemical Assay Reagents

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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