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Products Details
Product Description
– RMM-46 is a selective and reversible covalent inhibitor for MSK/RSK-family kinases[1].
Web ID
– HY-116533
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H26N4O5
References
– [1]Miller RM, et al. Electrophilic fragment-based design of reversible covalent kinase inhibitors. J Am Chem Soc. 2013 Apr 10;135(14):5298-301.
CAS Number
– 1307896-46-3
Molecular Weight
– 450.49
SMILES
– O=C(/C(C#N)=C/C1=CC2=C(C=C1)NN=C2C3=CC(OC)=C(C(OC)=C3)OC)NC(C)(CO)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MAPKAPK2 (MK2)
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
