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Products Details
Product Description
– RmlA-IN-1 (Compound 8a) is a potent inhibitor of glucose-1-phosphate thymidylyltransferase (RmlA) with an IC50 of 0.073 μM. RmlA-IN-1 influences monosaccharide l-Rhamnose biosynthetic pathway. RmlA-IN-1 affects bacterial cell wall permeability[1].
Web ID
– HY-146549
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C18H18N4O4S
References
– [1]Xiao G, et al. Next generation Glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: An extended SAR study to direct future design. Bioorg Med Chem. 2021;50:116477.
CAS Number
– 1415030-78-2
Molecular Weight
– 386.42
SMILES
– CN(S(=O)(C1=CC=CC=C1)=O)C2=C(N(C(NC2=O)=O)CC3=CC=CC=C3)N
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
