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RMC-4529

SKU HY-115869-Get quote Category Tags , ,

Products Details

Product Description

– RMC-4529 has an IC50 value of 1.0 nM against p-4E-BP1-(T37/46) in mTOR kinase cellular assay.

Web ID

– HY-115869

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C90H139N13O23

References

– [1]Semko C, et al. Rapamycin analogs as mtor inhibitors. WO2018204416A1.

CAS Number

– 2250059-27-7

Molecular Weight

– 1771.14

SMILES

– NC1=C2C(C3=CC=C(OC(N)=N4)C4=C3)=NN(C2=NC=N1)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCN5C=C(N=N5)CO/N=C6[C@@H]([C@@H](/C(C)=C/[C@H]([C@@H](C[C@@](OC([C@@]7([H])N(CCCC7)C(C([C@@]8(O[C@](CC[C@H]8C)([H])C[C@@H](/C(C)=C/C=C/C=C/[C@H](C[C@H]/6C)C)OC)O)=O)=O)=O)([H])[C@H](C)C[C@H]9C[C@H]([C@@H](CC9)O)OC)OC)C)O)OC)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– mTOR

Pathway

– PI3K/Akt/mTOR

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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