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Products Details
Product Description
– RIPK1-IN-8 (example 16), an aminoimidazopyridine, is a potent and selective RIPK1 inhibitor with an IC50 of 4 nM. RIPK1-IN-8 has the potential for inflammatory diseases research[1].
Web ID
– HY-143726
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C26H24F2N6O3
References
– [1]Michael E. Mertzman, et al. Aminoimidazopyridines as kinase inhibitors. WO2019089442A1.
CAS Number
– 2319663-07-3
Molecular Weight
– 506.50
SMILES
– O=C(C1=CC(C2=NN3C(C=C2)=NC(NC(C)=O)=C3)=C(C)N=C1)NCC4=CC(F)=CC(F)=C4OCC5CC5
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– RIP kinase
Isoform
– RIPK1
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
