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Products Details
Product Description
– RIP2 kinase inhibitor 1 (compound 11) is a potent and selective receptor interacting protein 2 (RIP2) kinase inhibitor with an IC50 of 0.03 μM for RIP2 FP. RIP2 kinase inhibitor 1 is used for autoinflammatory disorders[1].
Web ID
– HY-133014
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H17N5O2S
References
– [1]Haffner CD, et al. Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors.ACS Med Chem Lett. 2019 Oct 11;10(11):1518-1523.
CAS Number
– 2380028-10-2
Molecular Weight
– 355.41
SMILES
– O[C@@H]1[C@H](C2)NC3=C(C(N)=O)C(C4=CC(N=CS5)=C5C=C4)=NN3C[C@H]2C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– RIP kinase
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
