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Riddelline
Products Details
Product Description
– Riddelline, a pyrrolizidine alkaloid, is a potent genotoxic agent. Riddelline induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver[1].
Web ID
– HY-122099
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H23NO6
References
– [1]J C Mirsalis, et al. In Vivo Measurement of Unscheduled DNA Synthesis and S-phase Synthesis as an Indicator of Hepatocarcinogenesis in Rodents. 5.097Q1 Cell Biol Toxicol. 1987 Jun;3(2):165-73.
CAS Number
– 23246-96-0
Molecular Weight
– 349.38
SMILES
– O=C(/C(CC([C@]1(O)CO)=C)=CC)O[C@@]2([H])[C@@]3([H])C(COC1=O)=CCN3CC2
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Natural Products
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