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RG7713
$77 – $1,320
Products Details
Product Description
– RG7713 (RO5028442) is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a).
Web ID
– HY-12981
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C25H28ClN3O2
References
– [1]Ratni H, et al. Discovery of highly selective brain-penetrant vasopressin 1a antagonists for the potential treatment of autism via a chemogenomic and scaffold hopping approach. J Med Chem. 2015 Mar 12;58(5):2275-89.
CAS Number
– 920022-47-5
Molecular Weight
– 437.96
Compound Purity
– 99.92
SMILES
– O=C(C1=CN(CCN(C)C)C2=C1C=CC(Cl)=C2)N3CCC4(C(C=CC=C5)=C5CO4)CC3
Clinical Information
– Phase 1
Research Area
– Neurological Disease; Endocrinology
Solubility
– DMSO : 20 mg/mL (ultrasonic)
Target
– Vasopressin Receptor
Isoform
– V1a ReceptorÂ
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
