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Revusiran
SKU
HY-132590-Get quote
Category Oligonucleotides
Tags Epigenetics;Neuronal Signaling, Neurological Disease, Small Interfering RNA (siRNA);Transthyretin (TTR)
Products Details
Product Description
– Revusiran (ALN-TTRSC) is a 1st-generation short interfering RNA, which directed against transthyretin (TTR) mRNA. Revusiran can be used for transthyretin (TTR)-mediated amyloidosis research[1].
Web ID
– HY-132590
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– N/A
References
– [1]Jessica E Sutherland, et al. Nonclinical Safety Profile of Revusiran, a 1st-Generation GalNAc-siRNA Conjugate for Treatment of Hereditary Transthyretin-Mediated Amyloidosis. Nucleic Acid Ther. 2020 Feb;30(1):33-49.
CAS Number
– 1438322-82-7
Molecular Weight
– N/A
SMILES
– [Revusiran]
Clinical Information
– Phase 3
Research Area
– Neurological Disease
Solubility
– 10 mM in H2O
Target
– Small Interfering RNA (siRNA);Transthyretin (TTR)
Pathway
– Epigenetics;Neuronal Signaling
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.