Download Files:
Products Details
Product Description
– Reverse transcriptase-IN-3 is a pyrimidine-5-carboxamide derivative, acts as an inhibitor of HIV-1. Reverse transcriptase-IN-3 shows potent activity against the HIV-1 wild-type and mutant strains[1].
Web ID
– HY-151938
Shipping
– Room temperature
Molecular Formula
– C28H31N7O4S
References
– [1]Feng D, et al. Disubstituted pyrimidine-5-carboxamide derivatives as novel HIV-1 NNRTIs: Crystallographic overlay-based molecular design, synthesis, and biological evaluation. Eur J Med Chem. 2022 Nov 22;246:114957.
Molecular Weight
– 561.66
SMILES
– CC1=CC(C#N)=CC(C)=C1OC2=C(C=NC(NC3CCN(CC3)C4=CC=C(C=C4)NS(=O)(C5CC5)=O)=N2)C(N)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
