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REV 5901

$74

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Products Details

Product Description

– REV 5901 is a competitive and orally active antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene release be involved[1][2].

Web ID

– HY-112532

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C22H25NO2

References

– [1]Inwegen RGV, et, al. REV 5901: an orally effective peptidoleukotriene antagonist, detailed biochemical/pharmacological profile. J Pharmacol Exp Ther. 1987 Apr;241(1):117-24.|[2]Anderson G, et, al. Effects of REV 5901, a 5-lipoxygenase inhibitor and leukotriene antagonist, on pulmonary responses to platelet activating factor in the guinea-pig. Br J Pharmacol. 1988 Aug;94(4):1115-22.

CAS Number

– 101910-24-1

Molecular Weight

– 335.44

SMILES

– OC(CCCCC)C1=CC=CC(OCC2=NC3=CC=CC=C3C=C2)=C1

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Leukotriene Receptor;Lipoxygenase

Pathway

– GPCR/G Protein;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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