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REV 5901
SKU
HY-112532-5mg
Category Reference compound
Tags GPCR/G Protein;Metabolic Enzyme/Protease, Inflammation/Immunology, Leukotriene Receptor;Lipoxygenase
$74
Only 1000 item(s) left in stock.
Products Details
Product Description
– REV 5901 is a competitive and orally active antagonist of leukotriene receptor, with a Ki of 0.7 μM. REV 5901 is also a 5-lipoxygenase inhibitor. REV 5901 can be used for the research of asthma in which leukotriene release be involved[1][2].
Web ID
– HY-112532
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H25NO2
References
– [1]Inwegen RGV, et, al. REV 5901: an orally effective peptidoleukotriene antagonist, detailed biochemical/pharmacological profile. J Pharmacol Exp Ther. 1987 Apr;241(1):117-24.|[2]Anderson G, et, al. Effects of REV 5901, a 5-lipoxygenase inhibitor and leukotriene antagonist, on pulmonary responses to platelet activating factor in the guinea-pig. Br J Pharmacol. 1988 Aug;94(4):1115-22.
CAS Number
– 101910-24-1
Molecular Weight
– 335.44
SMILES
– OC(CCCCC)C1=CC=CC(OCC2=NC3=CC=CC=C3C=C2)=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Leukotriene Receptor;Lipoxygenase
Pathway
– GPCR/G Protein;Metabolic Enzyme/Protease
Product type
– Reference compound
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