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Product Description
– Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors[1][2][3][4][5][6].
Web ID
– HY-14649G
Shipping
– Room temperature
Molecular Formula
– C20H28O2
References
– [1]Rohwedel J, et al. Induction of cellular differentiation by retinoic acid in vitro. Cells Tissues Organs. 1999;165(3-4):190-202.|[2]Sherman MI, et al. Differentiation of early mouse embryonic and teratocarcinoma cells in vitro: plasminogen activator production. Cancer Res.|[3]Kelley MW, et al. Retinoic acid promotes differentiation of photoreceptors in vitro. Development. 1994 Aug;120(8):2091-102.|[4]Påhlman S, et al. Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation. Cell Differ. 1984 Jun;14(2):135-44.|[5]Sidell N. Retinoic acid-induced growth inhibition and morphologic differentiation of human neuroblastoma cells in vitro. J Natl Cancer Inst. 1982 Apr;68(4):589-96.|[6]Hyatt GA, et al. Retinoic acid alters photoreceptor development in vivo. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13298-303.
CAS Number
– 302-79-4
Molecular Weight
– 300.44
SMILES
– CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1
Clinical Information
– Phase 3
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RAR/RXR
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
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