Products Details

Product Description

– Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors[1][2][3][4][5][6].

Web ID

– HY-14649G

Shipping

– Room temperature

Molecular Formula

– C20H28O2

References

– [1]Rohwedel J, et al. Induction of cellular differentiation by retinoic acid in vitro. Cells Tissues Organs. 1999;165(3-4):190-202.|[2]Sherman MI, et al. Differentiation of early mouse embryonic and teratocarcinoma cells in vitro: plasminogen activator production. Cancer Res.|[3]Kelley MW, et al. Retinoic acid promotes differentiation of photoreceptors in vitro. Development. 1994 Aug;120(8):2091-102.|[4]PÃ¥hlman S, et al. Retinoic acid-induced differentiation of cultured human neuroblastoma cells: a comparison with phorbolester-induced differentiation. Cell Differ. 1984 Jun;14(2):135-44.|[5]Sidell N. Retinoic acid-induced growth inhibition and morphologic differentiation of human neuroblastoma cells in vitro. J Natl Cancer Inst. 1982 Apr;68(4):589-96.|[6]Hyatt GA, et al. Retinoic acid alters photoreceptor development in vivo. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13298-303.

CAS Number

– 302-79-4

Molecular Weight

– 300.44

SMILES

– CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1

Clinical Information

– Phase 3

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– RAR/RXR

Pathway

– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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