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Reticuline
$343 – $1,029
Products Details
Product Description
– Reticuline shows anti-inflammatory effects through JAK2/STAT3 and NF-κB signaling pathways. Reticuline inhibits mRNA expressions of TNF-α, and IL-6 and reduces the phosphorylation levels of JAK2 and STAT3[1]. Reticuline exhibits cardiovascular effects[2].
Web ID
– HY-N1356
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H23NO4
References
– [1]Yang X, et al. Anti-Inflammatory Effects of Boldine and Reticuline Isolated from Litsea cubeba through JAK2/STAT3 and NF-κB Signaling Pathways. Planta Med. 2018 Jan;84(1):20-25.|[2]Katy Lísias Dias, et al. Cardiovascular effects induced by reticuline in normotensive rats. Planta Med. 2004 Apr;70(4):328-33.
CAS Number
– 485-19-8
Molecular Weight
– 329.39
Compound Purity
– 98.91
SMILES
– OC1=CC2=C(C=C1OC)CCN(C)[C@H]2CC3=CC=C(OC)C(O)=C3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Endogenous Metabolite;JAK;NF-κB;STAT
Isoform
– Human Endogenous Metabolite;JAK2;NF-κB;STAT3
Pathway
– Epigenetics;JAK/STAT Signaling;Metabolic Enzyme/Protease;NF-κB;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
