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Retapamulin
$68 – $140
Products Details
Product Description
– Retapamulin (SB-275833) is a topical antibiotic that binds Staphylococcus aureus and E. coli ribosomes with a Kd of 3 nM.
Web ID
– HY-17010
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C30H47NO4S
References
– [1]Kircik LH.
Efficacy and tolerability of retapamulin 1% ointment for the treatment of infected atopic dermatitis: a pilot study.
J Drugs Dermatol. 2012 Jul 1;11(7):858-60.|[2]Candel FJ, Morales G, Picazo JJ.
In vitro activity of retapamulin against linezolid and methicillin-resistant Staphylococcus aureus isolates.
Rev Esp Quimioter. 2011 Sep;24(3):127-30.|[3]Pérez-Trallero E, Tamayo E, Montes M, GarcÃa-Arenzana JM, Iriarte V.
In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates.
Antimicrob Agents Chemother. 2011 May;55(5):2406-8.|[4]Weinberg JM, Tyring SK.
Retapamulin: an antibacterial with a novel mode of action in an age of emerging resistance to Staphylococcus aureus.
J Drugs Dermatol. 2010 Oct;9(10):1198-204.|[5]Retapamulin: focus on its use in the treatment of uncomplicated superficial skin infections and impetigo By Jacobs, Michael R.From Expert Review of Dermatology (2010), 5(5), 505-517.
CAS Number
– 224452-66-8
Molecular Weight
– 517.76
Compound Purity
– 98.0
SMILES
– C[C@@H]1[C@]23[C@](C(CC3)=O)([H])[C@]([C@H](OC(CS[C@@H]4C[C@@H]5N(C)[C@@H](CC5)C4)=O)C[C@](C=C)(C)[C@H]1O)([C@H](C)CC2)C
Clinical Information
– Launched
Research Area
– Others
Solubility
– DMSO : 110 mg/mL (ultrasonic)
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
