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RET-IN-7
$820 – $6,800
Products Details
Product Description
– RET-IN-7 demonstrates potent in vitro RET kinase inhibition and robust in vivo efficacy in RET-driven tumor xenografts upon multiday dosing in mice.
Web ID
– HY-141896
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H24ClFN6O2
References
– [1]Mathison CJN, et al. Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3-d]pyrimidine RET Inhibitors. ACS Med Chem Lett. 2021 Nov 6;12(12):1912-1919.
CAS Number
– 2763386-05-4
Molecular Weight
– 458.92
Compound Purity
– 98.00
SMILES
– O=C(NC12CCC(CC1)(CC2)N3C=C(C4=C3N=CN=C4N)C5=C(F)C=C(Cl)C(N)=C5)OC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
