Download Files:
Products Details
Product Description
– RET-IN-5 is a potent RET (rearranged during transfection) inhibitor with an IC50s of 0.4 nM and 135.1 nM for RET and VEGFR2, respectively (WO2021213476A1, compound 18)[1].
Web ID
– HY-145023
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C29H26FN9O
References
– [1]Pyrazolo[1,5-a]pyridine derivative, preparation method therefor, and composition and use thereof. WO2021213476A1.
CAS Number
– 2725770-20-5
Molecular Weight
– 535.57
SMILES
– N#CC1=C2C(C3=CN=C(N(C)[C@H](C4=CN=C(N5C=C(C=N5)F)C=C4)C)C=C3)=CC(OCC(C)(C)C#N)=CN2N=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
