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Products Details
Product Description
– RET-IN-26 (compound D5) is RET kinase inhibitor, with the IC50 of 0.33 μM[1].
Web ID
– HY-156471
Shipping
– Room temperature
Molecular Formula
– C23H27N5O2
References
– [1]Zhenzhu Li, et al. Design and synthesis of indol-2-one derivatives as potential RET inhibitors. Bioorganic & Medicinal Chemistry Letters Available online 29 October 2023, 129538
Molecular Weight
– 405.49
SMILES
– O=C1NC2=CC(C#N)=CC=C2/C1=C/C3=C(C)C(C(NCCN(CC)CC)=O)=C(C)N3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
