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Products Details
Product Description
– RET-IN-25 (compound 6b) is a RET kinase inhibitor with anticancer activity. RET-IN-25 inhibits medullary thyroid carcinoma (MTC) with IC50s of 3.6 μM (3 days) and 3.0 μM (6 days) against TT(C634R) MTC[1].
Web ID
– HY-156113
Shipping
– Room temperature
Molecular Formula
– C22H17N3O5S
References
– [1]La Monica G, et al. Design and Synthesis of Novel Thieno [3, 2-c] quinoline Compounds with Antiproliferative Activity on RET-Dependent Medullary Thyroid Cancer Cells[J]. ACS Omega, 2023.. . .
CAS Number
– 2965703-02-8
Molecular Weight
– 435.45
SMILES
– O=C(NC1=C(SC2=C1C=NC3=CC=C(C=C32)[N+]([O-])=O)C(OCC)=O)C4=CC=C(C)C=C4
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
