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Products Details
Product Description
– RET-IN-17 is a potent inhibitor of RET. RET-IN-17 has the potential for the research of pain associated with IBS and other gastrointestinal disorders and for the research of cancers with constitutive RET kinase activity (extracted from patent WO2016038552A1, compound 1)[1].
Web ID
– HY-147563
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H28F4N4O4
References
– [1]Michael P. Demartino, et al. Pyridone derivatives as rearranged during transfection (ret) kinase inhibitors. Patent WO2016038552A1.
CAS Number
– 1885880-08-9
Molecular Weight
– 548.53
SMILES
– CCOC1=CC(NC=C1C2=CC(F)=C(C=C2)CC(NC3=CC(C(NCCN(C)C)=O)=CC(C(F)(F)F)=C3)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
