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Products Details
Product Description
– RET-IN-13 (compound 1), a quinoline compound, is a potent RET inhibitor with IC50s of 0.5 nM, 0.9 nM for RET (WT) and RET (V804M), respectively. RET-IN-13 has the potential for tumors or intestinal diseases related to abnormal activation of RET research[1].
Web ID
– HY-144029
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C32H33F4N5O3
References
– [1]Jiansong Wang, et al. Quinoline compounds. WO2021164742A1.
CAS Number
– 2684258-54-4
Molecular Weight
– 611.63
SMILES
– O=C(CC1=CC=C(C2=CN=C3C=C(C(OC)=CC3=C2)OC)N=C1)NC4=C(F)C=C(CN5CCN(CC5)CC)C(C(F)(F)F)=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
