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RET-IN-12
Products Details
Product Description
– RET-IN-12 (compound 2) is a RET inhibitor, with IC50 values of 0.3 nM and 1 nM for RET(WT) and RET(V804M), respectively[1].
Web ID
– HY-144030
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H30F3N5O4
References
– [1]ZHANG YANG (CN), et al. PHENYL BISAMIDE COMPOUND. Patent WO2021164741A1.
CAS Number
– 2684252-55-7
Molecular Weight
– 581.59
SMILES
– O=C(C1=CC(NC(CC2=CC=C(C3=CN=C4C=C(C(OC)=CC4=C3)OC)N=C2)=O)=CC(C(F)(F)F)=C1)NCCN(C)C
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.