Download Files:
Resomelagon (acetate)
$260 – $2,100
Products Details
Product Description
– Resomelagon (AP1189) acetate is a potent, orally active melanocortin receptor (MR) agonist about MC1 and MC3. Resomelagon acetate induces ERK1/2 phosphorylation and Ca2+ mobilization. Resomelagon acetate has anti-inflammatory activity. Resomelagon acetate can be used for obesity and chronic inflammation research[1][2].
Web ID
– HY-147301A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C16H18N6O4
References
– [1]Montero-Melendez T, et, al. Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol. 2015 Apr 1;194(7):3381-8.|[2]WHO Drug Information. International Nonproprietary Names for Pharmaceutical.
CAS Number
– 1809420-72-1
Molecular Weight
– 358.35
Compound Purity
– 99.75
SMILES
– N=C(N)N/N=C/C=C/C1=CC=CN1C2=C(C=CC=C2)[N+]([O-])=O.CC(O)=O
Clinical Information
– Phase 2
Research Area
– Metabolic Disease; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Melanocortin Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
