Remdesivir O-desphosphate acetonide impurity

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Products Details

Product Description

– Remdesivir O-desphosphate acetonide impurity is an impurity of Remdesivir. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity and is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro[1][2].

Web ID

– HY-136597

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C15H17N5O4

References

– [1]Dustin Siegel, et al. Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses. J Med Chem. 2017 Mar 9;60(5):1648-1661.|[2]Manli Wang, et al. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020 Mar;30(3):269-271.

CAS Number

– 1191237-80-5

Molecular Weight

– 331.33

Compound Purity

– 99.88

SMILES

– N#C[C@](O1)(C2=CC=C3N2N=CN=C3N)[C@@](OC4(C)C)([H])[C@@](O4)([H])[C@H]1CO

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– DNA/RNA Synthesis;SARS-CoV

Pathway

– Anti-infection;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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