Refametinib (R enantiomer)

SKU HY-10216-Get quote Category Tags , ,

Products Details

Product Description

– Refametinib R enantiomer is a MEK inhibitor extracted from patent WO2007014011A2, compound 1022, has an EC50 of 2.0-15 nM.

Web ID

– HY-10216

Shipping

– Room temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C19H20F3IN2O5S

References

– [1]Andreas Maderna, et al. N-(arylamino)-sulfonamide inhibitors of mek. WO 2007014011 A2.

CAS Number

– 923032-38-6

Molecular Weight

– 572.34

SMILES

– O=S(C1(C[C@H](CO)O)CC1)(NC(C(NC(C(F)=C2)=CC=C2I)=C3F)=C(OC)C=C3F)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– MEK

Isoform

– MEK

Pathway

– MAPK/ERK Pathway

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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