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Products Details
Product Description
– Rauwolscine is a selective α2-adrenoceptor antagonist that inhibits tumor growth and induces apoptosis[1].
Web ID
– HY-12710
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C21H26N2O3
References
– [1]A Bruzzone, et al. Alpha2-adrenoceptor action on cell proliferation and mammary tumour growth in mice. Br J Pharmacol. 2008 Oct;155(4):494-504.|[2]S La Marca, et al. The alpha-2 antagonists idazoxan and rauwolscine but not yohimbine or piperoxan are anxiolytic in the Vogel lick-shock conflict paradigm following intravenous administration. Life Sci. 1994;54(10):PL179-84.
CAS Number
– 131-03-3
Molecular Weight
– 354.44
SMILES
– [H][C@@]12[C@](CC[C@@H]([C@H]2C(OC)=O)O)(CN(CCC3=C4NC5=CC=CC=C53)[C@]4(C1)[H])[H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
