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Raptinal
$100 – $160
Products Details
Product Description
– Raptinal, a agent that directly activates caspase-3, initiates intrinsic pathway caspase-dependent apoptosis. Raptinal is able to rapidly induce cancer cell death by directly activating the effector caspase-3, bypassing the activation of initiator caspase-8 and caspase-9[1][2].
Web ID
– HY-121320
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H18O2
References
– [1]Yanheng Chen, et al. <i>H. pylori</i> infection confers resistance to apoptosis via Brd4-dependent <i>BIRC3</i> eRNA synthesis. Cell Death Dis. 2020 Aug 21;11(8):667. |[2]Rahul Palchaudhuri,et al. A Small Molecule that Induces Intrinsic Pathway Apoptosis with Unparalleled Speed. Cell Rep. 2015 Dec 1;13(9):2027-36.
CAS Number
– 1176-09-6
Molecular Weight
– 386.44
Compound Purity
– 98.0
SMILES
– O=CC1(C2(C=O)C3=C(C4=C2C=CC=C4)C=CC=C3)C5=C(C6=C1C=CC=C6)C=CC=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Apoptosis;Caspase
Isoform
– Caspase 3
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
